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Edler P, Schwab LSU, Aban M, Wille M, Spirason N, Deng Y-M, et al

In a world that seems increasingly full of stressors, glutathione has become a growing focus among researchers studying healthy aging, resilience, and long term vitality

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This provides direct cellular and molecular evidence for understanding the mechanisms of ferroptosis imbalance in AKD and CKD pathogenesis while offering crucial theoretical and data support for subsequent intervention strategies targeting ferroptosis-promoting pathways in kidney diseases (e.g., cell type-specific iron metabolism modulation and lipid peroxidation inhibition)

Inhibition of HDAC enhances STAT acetylation, blocks NF-B, and suppresses the renal inflammation and fibrosis in Npr1 haplotype male mice