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In the meantime, exogenous GLP-1 maintains its ability to act on the brainstem and hypothalamus by direct action

2 for all five dosing schedules, and semaglutide AUC 024h and C max on Day 10 (from 024 h after the last dose) by dosing schedule are displayed in Fig

Subsequently, 1 g of RNA was utilized for cDNA synthesis, and gene expression was evaluated through quantitative polymerase chain reaction (Q-Rex, Qiagen, Hilden, Germany), following previously outlined procedures [15]

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