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Early-phase clinical trials including a Phase 2 dose-ranging study published in the New England Journal of Medicine (2023) have demonstrated significant potential for weight reduction and metabolic improvement, generating considerable scientific interest

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801 KMT2B promotes RFK transcription by upregulating H3 methylation levels, thus activating the TNF-/NOX2 pathway, promoting ferroptosis and aggravating myocardial infarction size

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