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Beyond sleep, combined estrogen and progesterone therapy has been linked to improvements in insulin sensitivity and lipid profiles in women during early menopause [22], adding a further layer of metabolic benefit to the combination

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I describe the diagnostic criteria that distinguish bipolar I from bipolar II, including mania and hypomania and the different patterns of mood cycling

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In addition, hierarchical clustering revealed 26 core transcription factors predicted to be key driver genes of the HD progression 23 enriched particularly in the 3 month iSPN + mut population (Extended Data Fig