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To this point, a review and meta analysis of 11 trials demonstrated significant improvements in various high-intensity exercise performance measures including time to exhaustion, work capacity, peak power, and number of repetitions and volume lifted in leg press exercises (2)

Regardless of the etiology, plasma concentrations of free carnitine 20 mol/L and increased acylcarnitine/free carnitine ratios (0.4) are considered abnormal (6)

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Supplements containing a mixture of the D- and L-isomers (D,L-carnitine) have been associated with muscle weakness in patients with kidney disease