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Food and Drug Administration (FDA) under clearance number K252670

The product is supplied for in-vitro laboratory characterization only and is not for human or veterinary use

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Kalaany and Sabatini had shown in NOD-SCID (non-obese diabetic, severe combined immunodeficient) mice that xenografted tumors with constitutive activation of AKT by either gains in PIK3CA or loss of PTEN are resistant against CR, and insensitive to insulin and IGF-1 treatment in vitro