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Smart Image Examples Embodiment 1 [0087] Example 1: Preparation of Intermediate a [0088] Weigh Boc-Ala-OH (9.5 g, 50 mmol), HBTU (19.0 g, 55 mmol) and HOBT (8.1 g, 50 mmol) and dissolve in 250 mL of acetonitrile, add DIPEA (13.5 mL, 100 mmol), and activate at room temperature for 5 mins

This is where a dilute solution of acetic acid (usually 10% to 25% ) comes to the rescue

It's about finding that sweet spot where your lab values and your well-being align

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Muscle loss is a significant concern, given tirzepatide's better lean mass preservation data