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Incretin mimetics have demonstrated safety and efficacy in advanced kidney disease, however multiple studies have shown that use of GLP1-RA have shown improvements in glycemic control, body weight reductions, improved beta cell function, and decreased incidence hypoglycemia as compared to DPP4i in a general diabetes population 26,27,28,29,30,31 , effects which might explain the reduction of acute healthcare utilization observed in this study of patients with CKD treated with GLP1-RA as compared to DPP4i

That variation comes down to many factors, including age, baseline body composition, comorbid conditions, exercise, and the specific medication being used

Plus, if you're pushing through intense workouts or making major lifestyle changes, your body may simply be overstimulated

Tips to Support Better, More Consistent Results Take it consistently, every night

Studies have also indicated these medications carry a risk for thyroid cancer, prompting a warning on drug labels, but evidence is highly conflicting