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Tetany : Caused by simultaneous activation of all nerve cells, often due to low calcium levels, resulting in widespread muscle cramps
Concurrently, altered glucose metabolism in the orbitofrontal cortex and limbic regions reflects energy deficits and mitochondrial dysfunction, contributing to the severity of psychiatric symptoms, such as paranoia, agitation, and mood disturbances ( MRI studies have further identified gray matter atrophy in the prefrontal cortex, medial cingulate gyrus, and hippocampus, regions that are critically involved in memory, decision-making, and emotional regulation (Thompson et al., 2004)
Analytical error reduction using single point calibration for accurate and precise metabolomic phenotyping
So yeah, the shortage isn't necessarily being caused by a lack of active ingredients, but just a lack of injector pens