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The dimeric form of the band 3 protein, interacts with adducin to link with the junctional complex that connects the cytoskeleton to the membrane

Giasson BI, Duda JE, Quinn SM, Zhang B, Trojanowski JQ, Lee VM (2002) Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein

Frequency: as needed

10.1016/j.ccell.2022.02.006 65 JeekP

The potential benefits of such treatment (long-term weight reduction, prevention of diabetes and diabetic complications, including cardiovascular events) need to be demonstrated in large clinical trials, but this earlier-stage population may provide unique chances to reveal benefits that cannot be shown at later stages, when the degree of tissue damage has advanced to an irreversible state