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Dose optimization: Genetic polymorphism testing for CYP2D6 enzyme activity is required to guide dose adjustment, preventing excessive HPA axis suppression that could lead to abnormally low cortisol levels

Gallbladder issues: Rapid weight loss and high hormone levels can lead to gallstones or inflammation

Synthetic analogue of endogenous -MSH designed for increased stability and prolonged activity

Terns Pharmaceuticals expects to release initial 28-day data from that trial in the second half of 2024, the company's head of research and development, Erin Quirk, said during the conference

Lifestyle changes can help with constipation