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Serious Adverse Events Serious adverse events were relatively uncommon and did not show a clear dose-response signal

doi:10.1016/s0140-6736(78)92379-6

Even if a person is not deficient in Vitamin B12, as defined by a blood test, the symptoms of a B12 deficiency may include: Feeling weak or tired Problems with vision Headaches Pins and needles Reduced mental functions Wish to check you vitamin B12 levels

Together with serum cobalamin concentration, it can also be useful to monitor serum MMA levels, since MMA reflects the actual bioavailability of the vitamin

Gently swirl never shake or vortex as this denatures the 191aa protein