Folia Neuropathol (2013) 51(1):19
While mild, fleeting gut symptoms are normal, some rarer cases involve symptoms that dont go away
And the medication becomes ineffective, sometimes partially, sometimes completely
J Clin Endocrinol Metab 104:47564768 Paccou J, Tsourdi E, Meier C, Palermo A, Pepe J, Body JJ, Zillikens MC (2022) Bariatric surgery and skeletal health: a narrative review and position statement for management by the European Calcified Tissue Society (ECTS)
From 2008-2010, Sanofi-Aventis Acomplia (selective CB1 antagonist) and Abbott Laboratories Meridia (NE/5-HT reuptake inhibitor)--both also designed to suppress appetite--were pulled from the market over similar cardiac safety concerns