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[ Randomized controlled trial, general recommendation ] Recent meta-analyses of RCTs and cohort studies involving SGLT2 inhibitors revealed approximately a two-fold increased risk of DKA in people on SGLT2 inhibitors compared to those on placebo or other glucose lowering medications [817,818]

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CJC-1295 (no-DAC) was developed by ConjuChem in the early 2000s as a stabilised GHRH analogue, with four amino-acid substitutions to the native GHRH 1-29 sequence that resist proteolytic degradation

2014;3:CD005195