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Investigacion Clinica, 59(3), 230-241

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Moreover, these hormones contribute to beta cell proliferation and longevity, which is particularly relevant in type 2 diabetes where beta cell function is compromised

Trial exclusion patterns Phase 2 and Phase 3 retatrutide trials commonly excluded participants with a history of pancreatitis, medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2 (MEN 2), severe gastroparesis, recent major cardiovascular events, severe kidney impairment, type 1 diabetes (in the obesity studies), and pregnancy or breastfeeding

Guixeres-Esteve T, Ponce-Zann F, Morales JM, Lurbe E, Alvarez-Pitti J, Monlen D