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Causal Inference : What If (CRC Press, 2010)

Each step up brings a temporary intensification of side effects as your body adapts to the higher receptor activation

Nauck MA, Homberger E, Siegel EG, Allen RC, Eaton RP, Ebert R, Creutzfeldt W: Incretin effects of increasing glucose load in man calculated from venous insulin and C-peptide responses

Episodes of sinus tachycardia (associated with a concomitant increase from baseline in heart rate of at least 15 beats per minute) were reported in up to 23% of patients