Results Non-lesional vitiligo melanocytes show increased expression of autophagic markers To investigate the possible involvement of autophagy in vitiligo, we initially determined the relative mRNA abundance of some Atg transcripts ( Atg5, Atg7, Atg8 ) by quantitative reverse-transcriptase PCR (Fig
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4, 5, 6 This is also the case for other Ang fragments: the heptapeptide Ang-(17), which is processed from Ang I by tissue endopeptidases, 7 and the octapeptide Ang A, which is generated from Ang II by enzymatic decarboxylation of Asp
Each producing overlapping symptoms but requiring different management approaches