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As the effects of the medication diminish, some individuals experience rebound, a sudden drop in energy levels, severe hunger and low or depressed mood
A review by Verma and colleagues (2025) explored how skin-derived Bifidobacterium may influence the production of glucagon-like peptide-1 (GLP-1), a hormone known for regulating blood sugar and protecting cells from damage
The development of next-generation oral GLP-1 agents with improved bioavailability enabling the higher systemic drug exposures needed to match injectable efficacy is the key technical milestone that will determine how much of the injectable market oral formulations can ultimately capture
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