Pasiakos, Stefan M., et al
You can also experience sleep loss from other side effects, like GI issues and anxiety. Dr
Group A (semaglutide group): Patients treated with semaglutide (0.5 mg) along with other oral antidiabetic drugs (sulfonylureas, metformin, DPP-4 inhibitor, or SGLT-2 inhibitor), or insulin, or both Group B (without semaglutide): Patients treated with other oral antidiabetic drugs (sulfonylureas, metformin, DPP-4 inhibitor, or SGLT-2 inhibitor), or insulin, or both
Studies in mice with CNS neuron-specific GLP-1R knockout showed that liraglutide failed to induce weight loss but still improved glucose levels, suggesting that brain GLP-1Rs are necessary for the weight-lowering effect of GLP-1RAs but not essential for their glucose-lowering effects (142)
4 Alonso-MagdalenaP.VieiraE.SorianoS.MenesL.BurksD.QuesadaI.et al (2010)