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Confocal fluorescence images were acquired on FV1000 (Olympus)

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in addition to varying experimental conditions, species differences may account for some of the discrepancies observed

Studies have found that GLP-1R is widely distributed on pancreatic and other tissues and has multiple biological effects, such as reducing neuroinflammation, promoting nerve growth, improving heart function, suppressing appetite, delaying gastric emptying, regulating blood lipid metabolism, and reducing fat deposition