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Most reviews conclude that while the mechanistic rationale is plausible, the current evidence is insufficient to support routine use of inositol for mental health conditions.20 38 Inositol supplements appear to work by supporting intracellular signaling rather than acting as a direct hormone or drug-like agent

And so, GLP-1 therapies improve weight, blood sugar and lipid profiles, and some have demonstrated cardiovascular event reduction in high-risk populations, which makes them particularly relevant for patients with RA who also have diabetes or obesity-related cardiovascular risk

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