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The Phase 2 trials enrolled people with a BMI of 27 or higher with at least one weight-related condition, or a BMI of 30 or higher without additional conditions

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The proportion of eosinophilic granulocytes ( Figure 4C ) decreased significantly from d 42 ap (CAR 11%, CON 12%) until 4 h pp (CAR 0.3%, CON 0.2%) and recovered slightly until 24 h pp to a level that remained unchanged until the end of the trial

Dambrova M, Zuurbier CJ, Borutaite V, Liepinsh E, Makrecka-Kuka M