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Comparative effectiveness of GLP1 receptor agonists on glycaemic control, body weight, and lipid profile for type 2 diabetes: systematic review and network meta-analysis

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One model for this rewriting of the epigenome is the presence of so-called memory domains where pioneer TF binding to nucleosomes in response to stimuli opens up chromatin in stress-responsive loci and allows epigenetic writers to remodel the chromatin to allow it to remain open after the stimuli are removed 32