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doi: 10.3389/fendo.2019.00389 Received 07 April 2019 Accepted 30 May 2019 Published 19 June 2019 Volume 10 - 2019 Edited by Jens Juul Holst, University of Copenhagen, Denmark Reviewed by Leon Bach, Monash University, Australia

Patients should be aware of the associated potential risks due to the lack of data available about its use

Nature 534 , 710713 (2016)

Nootropics may include dietary supplements, herbs, nutrients, synthetic compounds, prescription drugs, research chemicals, and other substances with very different safety, legal, and regulatory profiles

Increased expression of type 2 3-hydroxysteroid dehydrogenase/type 5 17-hydroxysteroid dehydrogenase (AKR1C3) and its relationship with androgen receptor in prostate carcinoma