Cardinal KM, De Moraes ML, Borille R, Lovato GD, Ceron MS, Vilella LDM, et al
Incorrect dosing compromises data reproducibility and may shift subjects into different dose-response ranges, invalidating comparisons across study groups
Youll need to show that you still meet all four of the requirements above, plus one additional requirement : that youve lost at least 5% of your body weight since starting treatment with Wegovy
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3.5.2 GLP-1 modulation within reward networks and downregulation of motivation The reward network can be conceptualised as a distributed circuit involving the ACC, OFC, ventral striatum, ventral pallidum, and midbrain dopaminergic systems, with additional modulation by structures such as the amygdala and hippocampus (54, 55)