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Though pathogenic RFK mutations are rare, animal models have shown that RFK loss results in impaired mitochondrial electron transport, NF-B activation, cognitive decline, and neuroinflammation, highlighting its disease relevance

This matters in the current tirzepatide enforcement environment because the FDA compounding shutdown and Eli Lilly lawsuits primarily target entities producing tirzepatide for human use

However, rules are evolving, and some situations may allow limited support when a patient has very high true out-of-pocket drug costs or lacks access to the medication through their health plans

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This amounts to about 80 to 110 grams of protein a day for most people