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Most show a smaller measured effect than exercise or the prescription options

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Duration: 16-24 weeks for significant fat loss, can extend longer with medical supervision Expected timeline: Week 1-4: Appetite reduction, initial weight loss beginning Week 4-12: Consistent fat loss of 1-2 pounds weekly Week 12-24: Significant body composition transformation Cost estimate: $300-600 per month depending on semaglutide source See the peptides for weight loss guide for comprehensive information

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A 2022 reference values study in 346 healthy adults aged 18-85 established normative ranges