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If switching is not possible or not preferred, a pragmatic approach involves increasing oral progesterone from 100 mg to 200 mg daily for the first 4-6 weeks of semaglutide treatment

Fat loss during GLP-1RA treatment is associated with varying degrees of muscle mass loss [24,162]

Peer review Peer review information Nature Communications thanks Nicolas Rouhier and Mirko Zaffagnini for their contribution to the peer review of this work

Limitations: It has relatively low sensitivity and is not suitable for samples with strong antibacterial properties

Sources of fiber include pharmacologic or dietary supplementation