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GLP-1 medications are not proven to directly treat acne, but the weight loss and improved insulin sensitivity they produce may indirectly benefit some patients by reducing androgen levels and sebum production

The weight loss curves had not plateaued at week 26, suggesting that longer treatment periods would yield even greater reductions

Moreover, significantly reduced glomerulosclerosis, vascular endothelium, and tubular serious injuries, with considerable preservation of serum waste substances, DNA breakage, and normalization of protein profiles, hematological parameters, MDA concentration, and antioxidant enzyme levels (6, 17)

2001 Oct;119(10):1417

doi:10.1016/S0016-5085(03)00216-6 163