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The first generation of GLP-1 therapies exhibit reduced susceptibility to enzymatic degradation, while providing effective glucose control, improved -cell function, body weight loss and decreased systolic blood pressure in patients with T2D (Meier, 2012) The newly developed incretin mimetics, including albiglutide, dulaglutide and semaglutide, are designed to have extended pharmacokinetic profiles and efficacy suitable once-weekly administration

The best strategy is never letting the vial reach damaging temperatures in the first place

In adults with overweight or obesity who completed a 20-week run-in on semaglutide 2.4 mg, mean weight fell by 10.6% before randomisation

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Patients who combine GLP-1 therapy with CGM monitoring tend to make smarter lifestyle choices and see better outcomes