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In the acute administration paradigm, animals received a single intraperitoneal infusion (over 30 minutes) of cisplatin at doses ranging from 9 mg/kg to 15 mg/kg, and were monitored for up to 7 days

Several chromosomal abnormalities (mainly of chromosomes 1 and 11) have been identified in PRLomas and were more numerous in more aggressive tumors

After decalcification, samples are rinsed in PBS, then are dissected carefully to remove the residual bone from the tissue so that just the attachment of the cochlear duct to the modiolar core is remaining

The longer term benefits will take a while to evaluate, but I do trust the process

(Table 2)