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Qsymia (phentermine/topiramate) Phentermine is an appetite suppressant

At Kingwood Urgent Care Clinic, we understand that achieving and maintaining a healthy weight can be challenging, even with dedicated diet and exercise efforts

Accessed August 12, 2023

For people on lower doses like the starting 2.5 mg dose , this trough can drop below the threshold needed for meaningful appetite suppression

Topiramates effect on weight reduction and long-term maintenance of body weight may be due to its effects on both appetite suppression and satiety enhancement, induced by a combination of pharmacologic effects including augmenting the activity of the neurotransmitter gamma-aminobutyrate, modulation of voltage-gated ion channels, inhibition of AMPA/kainite excitatory glutamate receptors, or inhibition of carbonic anhydrase