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The main pathological changes in psoriasis include excessive keratinocyte proliferation, epidermal hyperplasia, and increased neoangiogenesis, accompanied by inflammatory cell infiltration (Luo et al., 2020

Dose and route heterogeneity: animal studies use very variable doses (from 10 nanograms to 10 micrograms per kg) and different routes (intraperitoneal, subcutaneous, intravenous, oral), which complicates comparisons between protocols and establishing a clear dose-response relationship

Tissue Repair & Regeneration Extensive Research Preclinical studies have demonstrated remarkable acceleration of healing across multiple tissue types including skeletal muscle tears, tendon injuries, ligament damage, and bone fractures

Site-specific nitrosoproteomic identification of endogenously -nitrosylated proteins in Arabidopsis