[3,5] The day of weekly administration can be changed, if necessary, as long as the time between the two doses is at least 3 days (72 hours) [1] Storage Store in refrigerator Pens can be stored at room temperature for up to 21 days [1] LONG-TERM SAFETY Tirzepatide was FDA-approved in 2022
these drugs should not be used in patients with a personal or family history of medullary thyroid carcinoma or MEN2 Rare cases of retinopathy progression in patients with pre-existing severe diabetic retinopathy, likely related to rapid glycemic improvement Potential drug interactions related to delayed gastric emptying, which can affect absorption of other oral medications The practical approach is dose titration
The sales data, from market tracker PharmaTrac, marks an inflection point
Surgical procedures are best performed once your weight has stabilized and youve reached or are very close to your goal weight
[5] For women taking tirzepatide with oral contraceptives, backup contraception may be advised during dose escalation due to potential reduced contraceptive exposure
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