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As discussed above, EEG-based measurements, including basal state analyses and ERPs, may be useful as tools to evaluate the therapeutic efficacy of these compounds

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Biochem Cell Biol (2017) 95(1):14854.10.1139/bcb-2016-0061 149 NaiduASArnoldRR

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Animal Model:Neonatal Sprague-Dawley rats (male, 18-22g, postnatal day 7), hypoxic-ischemic brain damage (HIBD) model [2] Dosage:100 mg/kg Administration:Intraperitoneal injection, once daily, for 14 consecutive days starting 24 hours after HIBD induction Result:Brain injury: Reduced infarct volume by 40% compared to the HIBD control group as measured by triphenyltetrazolium chloride (TTC) staining