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So, while the body might absorb sufficient amounts into the blood, it is unable to absorb it into the tissues where its ultimately needed
That is an important framing for anyone tempted to treat it as a shortcut: even in the animal work that generates the interest, the compound is one input alongside energy balance, not a replacement for it
However, B12 injections are not a treatment for insomnia, depression, or anxiety on their own
It has also been shown to lower homocysteine levels, a molecule linked to inflammation and cognitive decline, with longitudinal studies linking optimal B12 levels with improved cognitive function, mood and reduced risk of neurodegenerative disease