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Wu et al., 2020)

These may include: Upset stomach Heartburn Abdominal pain Vomiting Nausea Constipation Diarrhea Dizziness Fatigue Mild symptoms tend to resolve once the body starts to get used to the medication

Pregnant women, breastfeeding mothers, and people with kidney, liver, or severe respiratory problems should avoid glutathione, as improper supplementation can stress metabolic pathways and increase health risks

In the absence of SIRT4, a failure to undergo cell cycle arrest induced by DNA damage causes a delay in DNA repair and increased chromosomal instability, suggesting a tumor suppressor effect of SIRT4 151