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In addition, RRM2 may exert its regulatory role by activating EGFR/AKT

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Nicotinamide N-Methyltransferase Inhibitor

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These results suggest that increased hepatic glutathione consumption, due to decreased aldehyde detoxification capacity, can sensitize the Aldh2*2 KI homozygous mice to hepatic ferroptosis after the rapid aldehyde storm

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