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Studies on heart health and metabolism have shown that therapies based on incretin hormones have a role in lowering inflammation in people with obesity or type 2 diabetes

However, semaglutide has a much longer safety record and is currently the most widely prescribed weight loss injection worldwide.

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The paper, titled Semaglutide slows epigenetic aging in a randomized trial of HIV-associated lipohypertrophy, was published in Nature Communications, listed in the PubMed database in May of this year, and only picked up wider media attention in mid-July

The prescribing information for both forms of Wegovy includes a boxed warning regarding the risk of thyroid C-cell tumors observed in animal studies, although a causal link in humans has not been established