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74 The pathophysiology of APAP-induced liver injury involves a complex interplay of cellular events, with inflammasome activation emerging as a critical component of the inflammatory response

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In the present study, utilising the above-described novel, highly translatable two-session operant food intake paradigm, rhesus macaques were administered GLP-1R agonist Ex to elucidate how GLP-1R agonism differentially modulates homoeostatic feeding regulation, hedonic valuation and palatability-driven anticipation and decision making across the two daily feeding sessions

doi: 10.1016/j.jmgm.2025.108984 [DOI] [PubMed] [Google Scholar] 136.de Freitas KS, Squarisi IS, Acsio NO, et al

FDA just approved orforglipron (Foundayo), Eli Lilly's oral GLP-1 receptor agonist for obesity