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The same review notes the risk is higher for people on ACE inhibitors or ARBs, because those medicines change how your kidneys handle fluid loss

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Hepatic cytochrome P450 enzyme activity and renal clearance efficiency both decline with age, which could theoretically extend the dihexa half life in older subjects, but specific pharmacokinetic data stratified by age are not published for dihexa

doi:10.21037/atm-22-1459 As Sobeai HM, Alohaydib M, Alhoshani AR, et al