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On the other hand, the treatment policity estimand was used to evaluate the treatment effect for all randomized participants regardless of whether the trial was discontinued early or rescue medicien was used [2]

Notably, these alterations occur prior to the onset of inflammation and induce the upregulation of epithelial-derived cytokines such as thymic stromal lymphopoietin (TSLP) and interleukin-33 (IL-33), which subsequently activate the Th2 immune axis in a sustained manner (Jo et al., 2018

Moreover, RF achieved a higher result with a precision of 84.43%, recall of 84.57%, F1-score of 84.67%, G-measure of 81.1%, and accuracy of 85.89%

Incorporating treatments that target the root issues, such as insulin resistance, can significantly improve outcomes

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