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Subsequently, the efficient GSH-mediated release of DOX into the cytosol was observed (Figure 2) ( FIGURE 2 Thermo-responsive drug delivery Thermo-responsive hydrogels are relatively the most researched responsive hydrogel systems because they show exclusive properties in controlled drug delivery systems

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The Ser14 and Ser17 of Semaglutide form a network of hydrogen bonds involving the receptor residues Asn300, Arg299, and Thr298