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The prooxidant oxidative stress imbalance needs an antioxidant system able to balance it and the principal role in antioxidant defense is carried out by antioxidant enzymes, with the paramount involvement of small-molecule antioxidant compounds like GSH

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However, what many believe to be the key factor are the sulfur groups in glutathione, which represent the very core of its protective role

JJ Dugoua is a naturopathic doctor in Toronto and has a PhD in Pharmaceutical Sciences