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Hi, Im Jamie, Your Bariatric Dietitian & GLP-1 Advocate After having my own weight loss surgery (VSG in 2017) and experiencing my own ups and downsincluding 28 lbs of regain and resurfacing PCOS symptomsI turned to GLP-1 medications

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Below is the incidence of complaints as experienced by the 62 patients who received the maximum dose of retatrutide (12mg/weekly) [24]: Nausea 45% Vomiting 19% Constipation 16% Diarrhea 15% Cardiac arrhythmia 11% Fatigue 10% Increased pancreatic enzyme (lipase) levels 8% Injection site reactions 8% Liver problems 3% (2 participants) Pancreatitis 2% (1 participant) On the other hand, in a phase 3 study on liraglutide involving 2,487 patients receiving the peptide, the researchers reported reported the following side effects in the liraglutide group: Nausea 40.2% Diarrhea 20.9% Constipation 20.0% Vomiting 16.3% Dyspepsia 9.5% Upper abdominal pain 5.7% Injection site reactions 5.7% Cholelithiasis 1% (20 participants) Pancreatitis less than 1% (4 participants) The only serious side effects identified from the list were cholelithiasis and pancreatitis