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Some anecdotal reports suggest improved spontaneous arousal for 23 days post-dose, but controlled studies have not confirmed persistent effects beyond the 68 hour pharmacodynamic window.

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However, because of potential side effects like skin rashes or the reversion effect where results fade after stopping treatment, you must not attempt to self-medicate

David Dolivo, Northwestern University, United States Updates Copyright 2023 Khodeneva, Sugimoto, Davan-Wetton and Montero-Melendez

If you have a sensitive stomach, you can take it with a light snack, but try to avoid heavy, high-fat meals immediately before or after your dose