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As it has been suggested that NOX2 is important for the initial oxidative burst following SE that contributes to seizures in trauma and chemically induced epilepsy models (Zilberter et al., 2022), the efficacy of NOX inhibition in chronic epilepsy and in a clinically relevant window following a seizure inciting event needs further evaluation
A high-fiber diet synergizes with Prevotella copri and exacerbates rheumatoid arthritis
Haber, A
95 Interestingly, the gut microbiota is essential for microglial morphological and functional maturation, and microglial damage can be corrected to some extent by a complex microbiota
Second, individual variability in susceptibility to heat stress-induced damage calls for the development of personalized intervention strategies based on biomarkers of OS, such as 8-hydroxy-2-deoxyguanosine (8-OHdG) and ROS levels
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