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Weight loss varies by drug and dosetypically 5-10% with diabetes doses and potentially 15-20% with higher weight management doses over 68 weeks

57 , 140 , 161 In the absence of gastric ultrasound assessments, patients taking long-acting GLP-1 RAs within 4 weeks should be considered as having full stomachs and the anaesthetic plan, including proceeding with elective procedures, should be tailored accordingly

Hypersensitivity including injection site reactions have been associated with use, with reports of anaphylaxis and other rashes

The shortages also affected the availability of semaglutide for type 2 diabetes treatment, for which it was originally approved under the brand name Ozempic