According to a study published in April 2024, around 530 million adults around the world are affected by diabetes, with almost 98% of patients diagnosed with Type 2 diabetes
However, the B cell levels did not decline, and the number of CD5+ B cells increased
Preclinical and clinical data, though predominantly derived from case reports and small cohort studies to date, consistently indicate that GLP-1 RAs - including liraglutide, semaglutide, and the dual GIP/GLP-1 RA tirzepatide - can induce clinically meaningful weight loss, suppress the characteristic severe hyperphagia, and improve key cardiometabolic parameters in both heterozygous and homozygous MC4R variant carriers
Yerba mate has been shown to stimulate GLP-1 secretion in some studies, lending support to the drinks credited ability to promote weight loss
MMWR Morb Mortal Wkly Rep (2020) 69(30):9938