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Sarkaki A, et al

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Positive results from the Phase II WILLOW study and Phase III ASPEN study demonstrate that compared to placebo controls, DPP1 inhibition treatment can significantly extend time intervals to first acute exacerbations in bronchiectasis patients and effectively reduce overall acute exacerbation occurrence frequency (Chalmers et al., 2020

Duration: Many weeks to months, commonly 12 weeks or longer in human studies that demonstrated measurable increases in muscle carnitine

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